We worked very closely with the ICR team, organised numerous interviews, surveys, workshops and regular working sessions over a period of 6 months. Our work started by working with the heads of research to understand their needs in relation to the new Research Strategy. In parallel, we analysed the future income (including Monte Carlo simulation for future drug discovery income) and expenses to have a clear financial baseline for assessing the various options. We then started an analysis of the competitive environment and a review of internal capabilities (benchmarking, capability diagnostic) to identify current challenges and opportunity areas. This enabled us to select with the management team the key levers that the ICR could use and developed the new strategy and operating model. The last step was to develop an implementation plan for the change initiatives, finalise the business case and risk analysis, and define a governance model.